Hereditary Spastic Paraparesis

Hereditary spastic paraparesis affects both sexes and may begin at any age. It affects about 1 to 10 of 100,000 people.

This disorder has many forms and can result from many different types of genetic abnormalities. All forms cause degeneration of the nerve pathways that carry signals from the brain down the spinal cord (to muscles).

More than one area of the spinal cord may be affected.